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Merck
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Key Documents

AB5336P

Sigma-Aldrich

Anti-Synuclein α Antibody

Chemicon®, from sheep

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

sheep

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

rat, mouse, human

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable (paraffin)

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... SNCA(6622)

免疫原

Synthetic peptide corresponding amino acids 108-120 of human alpha synuclein.

應用

Anti-Synuclein Antibody, α is an antibody against Synuclein for use in IH(P).
Immunohistochemistry: 1:1,000 on frozen or paraffin sections.

Optimal working dilutions must be determined by the end user.

聯結

Replaces: 04-1053

外觀

Affinity purified immunoglobulin. Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any residue. Glycerol (1:1) can be added for additional stability.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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危險聲明

防範說明

危險分類

Aquatic Chronic 3

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Mohamed-Bilal Fares et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(7), E912-E921 (2016-02-04)
Lewy bodies (LBs) are intraneuronal inclusions consisting primarily of fibrillized human α-synuclein (hα-Syn) protein, which represent the major pathological hallmark of Parkinson's disease (PD). Although doubling hα-Syn expression provokes LB pathology in humans, hα-Syn overexpression does not trigger the formation
Aggresome-related biogenesis of Lewy bodies.
Kevin St P McNaught, P Shashidharan, Daniel P Perl, Peter Jenner, C Warren Olanow
The European Journal of Neuroscience null
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain.
Eslamboli, A; Romero-Ramos, M; Burger, C; Bjorklund, T; Muzyczka, N; Mandel, RJ; Baker et al.
Brain null
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct.
K A Conway, J C Rochet, R M Bieganski, P T Lansbury
Science (New York, N.Y.) null

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