推荐产品
生物源
rabbit
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human
製造商／商標名
Chemicon®
技術
immunohistochemistry: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... CX3CR1(1524)
一般說明
CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively (1-4). The seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by facktokine (6). CX3CR1 mediates leukocyte migration and adhesion.
免疫原
Synthetic peptide from the extracellular loop of human CX3CR1.
應用
Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, extracellular loop is an antibody against C-X-X-X-C Chemokine Receptor 1 for use in IH & WB.
Western blot: 1:500 (THP cell lysate can be used as positive control and an approximately 50 kDa band can be detected)
Immunohistochemistry in frozen sections
Optimal working dilutions must be determined by end user.
Immunohistochemistry in frozen sections
Optimal working dilutions must be determined by end user.
外觀
Format: Purified
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Impact of chemokine receptor CX3CR1 in human renal allograft rejection.
Hoffmann U, Bergler T, Segerer S, Rummele P, Kruger B, Banas MC, Reinhold S, Banas B, Kramer BK
Transplant Immunology null
Involvement of the fractalkine pathway in the pathogenesis of childhood hemolytic uremic syndrome.
Maria Victoria Ramos,Gabriela C Fernandez,Natasha Patey,Pablo Schierloh,Ramon Exeni et al.
Blood null
Expression of chemokine receptors predicts the site of metastatic relapse in patients with axillary node positive primary breast cancer.
Andre, F; Cabioglu, N; Assi, H; Sabourin, JC; Delaloge, S; Sahin, A; Broglio, K; Spano et al.
Annals of Oncology null
Expression of the fractalkine receptor (CX3CR1) in human kidney diseases.
Stephan Segerer, Erik Hughes, Kelly L Hudkins, Matthias Mack, Tracy Goodpaster, Charles E Alpers
Kidney International null
The role of capillary density, macrophage infiltration and interstitial scarring in the pathogenesis of human chronic kidney disease.
Eardley, KS; Kubal, C; Zehnder, D; Quinkler, M; Lepenies, J; Savage, CO; Howie, AJ; Kaur et al.
Kidney International null
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