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Key Documents

AB15417

Sigma-Aldrich

Anti-Beclin 1 Antibody

serum, Chemicon®

别名:

Coiled-coil myosin-like BCL2-interacting protein, BECN1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... BECN1(8678)

一般說明

Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. Beclin 1 is a BCL-2 interacting protein and this protein was shown to play a role in the promotion of autophagy.

特異性

Beclin 1 [Coiled-coil myosin-like BCL2-interacting protein, BECN1].

免疫原

Synthetic peptide corresponding to the C-terminus of human Beclin 1 protein.

應用

Detect Beclin 1 using this Anti-Beclin 1 Antibody validated for use in WB, IC, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western blot: 1:100-1:2,000
Immunocytochemistry: 1:100-1:2,000
Immunohistochemistry: 1:100-1:2,000
Optimal working dilutions must be determined by end user.

聯結

Replaces: MABN16

外觀

Serum
Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

儲存和穩定性

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids


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Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation.
Iwata, Atsushi, et al.
Proceedings of the National Academy of Sciences of the USA, 102, 13135-13140 (2005)

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