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品質等級
產品線
Novabiochem®
PEGA
形狀
beads
反應適用性
reaction type: Fmoc solid-phase peptide synthesis
製造商/商標名
Novabiochem®
應用
peptide synthesis
官能基
alcohol
儲存溫度
2-8°C
一般說明
This support consists of amino PEGA resin derivatized with Sheppard′s base-labile 4-hydroxymethylbenzoic acid linker [1]. For further information, please refer to the product entry for amino PEGA resin(855015). Note: PEGA resins are supplied swollen in ethanol, with 1g dry resin corresponding to approximately 15 mL of swollen resin. As the beads of PEGA resins become very sticky and easily damaged when shrunk or dried, they are best handled in a swollen state. To use, the appropriate amount of swollen resin should be weighed into a reaction vessel and any residual ethanol removed by copious washings with the appropriate solvent or solvent mixture. After peptide assembly, the resin should be washed with DCM and transferred to the cleavage vessel. Excess DCM can be removed under vacuum, and the shrunk resin treated with the TFA cocktail. The characteristics of the swollen resin, its robustness and high permeability enables its use in both batch and continuous flow synthesis apparatus.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] R. C. Sheppard, et al. (1982) Int. J. Peptide Protein Res., 20, 451.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] R. C. Sheppard, et al. (1982) Int. J. Peptide Protein Res., 20, 451.
聯結
Replaces: 01-64-0113
分析報告
Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.10 - 0.40 mmol/g
Swelling Volume (in DMF): lot specific result
dry resin %: lot specific result
The resin is sold swollen in ethanol.
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.10 - 0.40 mmol/g
Swelling Volume (in DMF): lot specific result
dry resin %: lot specific result
The resin is sold swollen in ethanol.
法律資訊
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
商品
Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.
Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.
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