8.52211

Fmoc-His(Mtt)-OH

Novabiochem^®

• 别名: Fmoc-His(Mtt)-OH, N-α-Fmoc-N-im-methyltrityl-L-histidine
• 经验公式（希尔记法）: C₄₁H₃₅N₃O₄
• CAS号: 133367-34-7
• 分子量: 633.73
• 分類程式碼代碼: 12352209
• NACRES: NA.22

属性

• 品質等級: 200
• 產品線: Novabiochem^®
• 化驗: ≥94.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• 形狀: powder
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• 應用: peptide synthesis
• 官能基: Fmoc
• 儲存溫度: 15-25°C
• InChI: 1S/C41H35N3O4/c1-28-20-22-31(23-21-28)41(29-12-4-2-5-13-29,30-14-6-3-7-15-30)44-25-32(42-27-44)24-38(39(45)46)43-40(47)48-26-37-35-18-10-8-16-33(35)34-17-9-11-19-36(34)37/h2-23,25,27,37-38H,24,26H2,1H3,(H,43,47)(H,45,46)/t38-/m0/s1
• InChI 密鑰: MNOCIIYDYLYWEU-LHEWISCISA-N

说明

一般說明

The Mtt group can be removed from the side-chain of histidine by treatment with dilute TFA ^[1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

^[1] K. Barlos, et al. (1991) Tetrahedron Lett., 32, 475.

聯結

Replaces: 04-12-1108

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 94.0 %
Water (K. F.): ≤ 5.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable