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Merck
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文件

8.52117

Sigma-Aldrich

Fmoc-Glu-O-2-PhiPr

Novabiochem®

别名:

Fmoc-Glu-O-2-PhiPr, N-α-Fmoc-L-glutamic acid α-2-phenylisopropyl ester

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About This Item

经验公式（希尔记法）:
C29H29NO6
CAS号:
207305-97-3
分子量:
487.54
分類程式碼代碼:
12352209
NACRES:
NA.22

品質等級

200

產品線

Novabiochem®

化驗

≥92.0% (acidimetric)
≥95% (TLC)
≥95.0% (HPLC)

形狀

powder

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商／商標名

Novabiochem®

應用

peptide synthesis

官能基

carboxylic acid

儲存溫度

15-25°C

相关类别

一般說明

An excellent tool for the synthesis of head-to-tail cyclic peptides by Fmoc SPPS [1]. The 2-PhiPr group can be selectively removed on the resin with 1% TFA in DCM in the presence of the standard t-butyl-based side-chain protecting groups.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Literature references

[1] F. Dick, et al. in ′Peptides 1996, Proc. of 24th European Peptide Symposium′, R. Ramage & R. Epton (Eds), Mayflower Scientific Ltd., Birmingham, 1998, pp. 339.

聯結

Replaces: 04-12-1284

分析報告

Colour (visual): white to yellow
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (DC(018A)): ≥ 95 %
Purity (TLC(0811)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): passes test
Assay (acidimetric): ≥ 92.0 %
Water (K. F.): ≤ 2.5 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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商品

Selecting Orthogonal Building Blocks

Novabiochem® product range has one of the largest collections of orthogonally and quasi-orthogonally protected tri-functional amino acids. These derivatives are useful tools for the synthesis of cyclic and branched peptides and peptides carrying side-chain modifications.

Selecting Orthogonal Building Blocks

Novabiochem® product range has one of the largest collections of orthogonally and quasi-orthogonally protected tri-functional amino acids. These derivatives are useful tools for the synthesis of cyclic and branched peptides and peptides carrying side-chain modifications.

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