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Key Documents

8.52108

Sigma-Aldrich

Fmoc-Ala-(Dmb)Gly-OH

≥97.0% (HPLC), for peptide synthesis, Novabiochem®

别名:

Fmoc-Ala-(Dmb)Gly-OH, N-α-Fmoc-L-alanyl-N-α-(2, 4-dimethoxybenzyl)-glycine

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About This Item

经验公式(希尔记法):
C29H30N2O7
分子量:
518.56
分類程式碼代碼:
12352209
NACRES:
NA.22

product name

Fmoc-Ala-(Dmb)Gly-OH, Novabiochem®

品質等級

產品線

Novabiochem®

化驗

≥90.0% (acidimetric)
≥97% (TLC)
≥97.0% (HPLC)

形狀

powder

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商/商標名

Novabiochem®

應用

peptide synthesis

官能基

Fmoc

儲存溫度

2-8°C

一般說明

Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides in Fmoc SPPS but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP® /DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS

聯結

Replaces: 04-12-1265

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -26.5 - -21.5 °
Purity (TLC(0811)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 2.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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