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Merck
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文件

8.51029

Sigma-Aldrich

N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms)

Novabiochem®

别名:

N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms), O-(N-Biotinyl-3-aminopropyl)-O′-(N-glutaryl-3-aminopropyl)-diethyleneglycol · DIPEA

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About This Item

经验公式(希尔记法):
C25H44N4O8S · xC8H19N
分子量:
560.70
分類程式碼代碼:
12352106
NACRES:
NA.22

品質等級

產品線

Novabiochem®

化驗

≥95.0% (HPLC)
≥98% (TLC)

形狀

powder

反應適用性

reaction type: Biotinylations

製造商/商標名

Novabiochem®

mp

131-136 °C

應用

peptide synthesis

儲存溫度

2-8°C

一般說明

The use of this novel biotin derivative incorporates a hydrophilic 20 atom PEG spacer between the peptide and biotin. This not only greatly improves the solubility of the resultant peptide, but reduces steric hindrance between the peptide and biotin, leading to better avidin binding and higher biological activity. The biotin-PEG derivative can be easily incorporated using any standard coupling method as the final step in SPPS, immediately prior to cleavage of the peptide from the resin.

Associated Protocols and Technical Articles

Biotinylation Reagents for Peptide Synthesis

聯結

Replaces: 01-63-0133

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (50 mg in 1 ml NMP): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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