8.21111

2-Thiazoline-2-thiol

for synthesis

• 别名: 2-Thiazoline-2-thiol, 2-Mercaptothiazoline
• 经验公式（希尔记法）: C₃H₅NS₂
• CAS号: 96-53-7
• 分子量: 119.21
• MDL號碼: MFCD00126013
• 分類程式碼代碼: 12352113
• 酶委員會索引編號: 202-512-1
• NACRES: NA.22

属性

• 品質等級: 200
• 形狀: powder
• 效力: 300 mg/kg LD₅₀, oral (Rat)
• pH值: 6-7 (20 °C, 10 g/L in H₂O)
• mp: 101-106 °C
• 儲存溫度: 2-30°C
• InChI: 1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
• InChI 密鑰: WGJCBBASTRWVJL-UHFFFAOYSA-N

说明

應用

• Inducing apoptosis in melanoma cells: A study described a ruthenium(II) complex with 2-mercaptothiazoline ligand inducing selective cytotoxicity by causing DNA damage and apoptosis specifically in melanoma cells, highlighting its potential as a therapeutic agent in oncology (de Melo et al., 2024).
• Antimicrobial and synergistic activities: Thiazoline derivatives, including compounds related to 2-mercaptothiazoline, were studied for their antimicrobial and synergistic effects with conventional antibiotics against multidrug-resistant Staphylococcus aureus, presenting a potential strategy for enhancing antibiotic efficacy (Khan et al., 2020).
• Antimicrobial investigation of metal complexes: The antimicrobial properties of Cd(II) and Sn(II) complexes with 2-mercaptothiazoline were evaluated, underscoring the compound′s role in enhancing the bioactivity of metal-based therapeutics (Gaber et al., 2021).

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P264 - P270 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable