573130

STAT3 Inhibitor VI, S3I-201

InSolution,≥95%

• 别名: InSolution STAT3 Inhibitor VI, S3I-201
• 经验公式（希尔记法）: C₁₆H₁₅NO₇S
• 分子量: 365.36
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: liquid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic); protect from light
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). The solid form of this compound (Cat. No. 573102) is also available.

包裝

Packaged under inert gas

警告

Toxicity: Irritant (B)

外觀

A 50 mM (5 mg/274 µl) solution of STAT3 Inhibitor VI, S3I-201 (Cat. No. 573102) in DMSO.

重構

Following initial thaw, aliquot and freeze (-20°C).

其他說明

Lin, L., et al. 2009. Oncogene, 28, 961.
Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA104, 7391.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 188.6 °F - closed cup - (refers to pure substance)
• 閃點（°C）: 87 °C - closed cup - (refers to pure substance)