跳转至内容
Merck
所有图片(2)

文件

16-256

Sigma-Aldrich

抗磷脂酰丝氨酸抗体,克隆1H6,Alexa Fluor 488

clone 1H6, Upstate®, from mouse

别名:

488-Alexa Fluor Antibody, Alexa Fluor 488 Detection, Clone 1H6 Anti-Phosphatidylserine

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

共軛

ALEXA FLUOR 488

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

1H6, monoclonal

物種活性

vertebrates

製造商/商標名

Upstate®

技術

flow cytometry: suitable

同型

IgG

運輸包裝

wet ice

目標翻譯後修改

phosphorylation (pSer)

一般說明

意义:
抗磷脂酰丝氨酸可用于检测膜磷脂磷脂酰丝氨酸(PS)从内膜小叶向外膜小叶的移位;它提供了膜联蛋白V的替代方法,用于定量细胞凋亡。
磷脂酰丝氨酸或PS是天然存在的磷脂营养素。PS对所有人体细胞的功能至关重要,但最集中在大脑中。它在该器官中的相对丰度反映了它已被证明参与了各种神经细胞功能,包括神经递质释放和突触活性。临床研究表明,PS可以支持随着年龄增长而下降的大脑功能。

特異性

识别细胞膜中的磷脂酰丝氨酸(PS)

免疫原

含有70%磷脂酰丝氨酸和30%磷脂酰甘油的脂质体。

應用

使用经验证可用于FC的抗磷脂酰丝氨酸抗体(克隆1H6,Alexa Fluor 488)检测磷脂酰丝氨酸。
研究子类别
凋亡-附加
研究类别
细胞凋亡 & 癌症

品質

流式细胞术: 0.2 μg该抗体可在固定Jurkat细胞中检测出磷脂酰丝氨酸(见第2页)。

凋亡测定:使用抗磷脂酰丝氨酸,克隆1H6,Alexa Fluor 488偶联物或膜联蛋白V FITC偶联物测量星形孢菌素对Jurkat细胞中凋亡诱导的时间过程。

外觀

纯化的小鼠单克隆IgG,溶于含有PBS、1% BSA、0.05%吐温和0.05%叠氮化钠的缓冲液中。 在4ºC为液体形式。
蛋白G纯化

儲存和穩定性

自收到之日起可稳定保存1年。

分析報告

对照
阴性对照:目录号16-240,正常小鼠IgG,Alexa Fluor 488-偶联物。

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

法律資訊

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Alexa Fluor是Molecular Probes, Inc.的注册商标。

除非在产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得对人或动物用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用。

Not finding the right product?  

Try our 产品选型工具.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Yuta Nakazawa et al.
eLife, 10 (2021-11-10)
Although tumor-infiltrating regulatory T (Treg) cells play a pivotal role in tumor immunity, how Treg cell activation are regulated in tumor microenvironments remains unclear. Here, we found that mice deficient in the inhibitory immunoreceptor CD300a on their dendritic cells (DCs)
Yi An et al.
Scientific reports, 11(1), 6392-6392 (2021-03-20)
Head and neck squamous cell carcinomas (HNSCC) induced by human papillomavirus (HPV) have increased recently in the US. However, the distinct alterations of molecules involved in the death pathways and drug effects targeting inhibitor of apoptosis proteins (IAPs) have not
Lazar Mandinov et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(11), 6700-6705 (2003-05-20)
The induction of an acute inflammatory response followed by the release of polypeptide cytokines and growth factors from peripheral blood monocytes has been implicated in mediating the response to vascular injury. Because the Cu2+-binding proteins IL-1alpha and fibroblast growth factor
P Nusbaum et al.
Biochemical Society transactions, 32(Pt3), 477-479 (2004-05-26)
CD43 down-regulation during the apoptosis of PMN (polymorphonuclear cells) is not caused by proteolysis or internalization. Could it be released with bleb-derived membrane vesicles? Membrane blebbing was followed by microscopy on PMN 'synchronized' by an overnight incubation at 15 degrees
Mark C Weir et al.
PloS one, 12(7), e0181178-e0181178 (2017-07-21)
Acute myelogenous leukemia (AML) is often associated with activating mutations in the receptor tyrosine kinase, Flt3, including internal tandem duplications (ITDs) within the regulatory juxtamembrane region. Previous studies have linked Flt3-ITD to the activation of the Fes protein tyrosine kinase

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门