推荐产品
生物源
mouse
品質等級
共軛
ALEXA FLUOR™ 488
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
4F11, monoclonal
物種活性
bovine, human, mouse, rat, hamster, avian
製造商／商標名
Upstate®
技術
flow cytometry: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
基因資訊
human ... CTTN(2017)
特異性
Recognizes Cortactin in rodent and human cells
免疫原
Mixture of affinity-purified tyrosine phosphoproteins from chick embryo fibroblasts expressing activated pp60src
應用
Detect Cortactin (p80/85) using this Anti-Cortactin (p80/85) Antibody, clone 4F11, Alexa Fluor 488 validated for use in FC, IF, WB & IC.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
品質
Routinely evaluated by immunoblot.
標靶描述
Mr 80kDa and in avian cells, Mr 80kDa and 85kDa
外觀
Protein G Purified
儲存和穩定性
1 year at 4°C from date of shipment
分析報告
Control
Negative Control: Catalog # 16-240, Normal Mouse IgG, ALEXA FLUOR™ 488-conjugate.
Negative Control: Catalog # 16-240, Normal Mouse IgG, ALEXA FLUOR™ 488-conjugate.
法律資訊
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Alexa Fluor is a registered trademark of Molecular Probes, Inc.
Alexa Fluor is a registered trademark of Molecular Probes, Inc.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
S A Weed et al.
Oncogene, 20(44), 6418-6434 (2001-10-19)
Exposure of cells to a variety of external signals causes rapid changes in plasma membrane morphology. Plasma membrane dynamics, including membrane ruffle and microspike formation, fusion or fission of intracellular vesicles, and the spatial organization of transmembrane proteins, is directly
M A McNiven et al.
The Journal of cell biology, 151(1), 187-198 (2000-10-06)
The dynamin family of large GTPases has been implicated in the formation of nascent vesicles in both the endocytic and secretory pathways. It is believed that dynamin interacts with a variety of cellular proteins to constrict membranes. The actin cytoskeleton
T Katsube et al.
The Journal of biological chemistry, 273(45), 29672-29677 (1998-10-29)
Cortactin is an actin filament-binding protein localizing at cortical regions of cells and a prominent substrate for Src family protein-tyrosine kinases in response to multiple extracellular stimuli. Human cortactin has been identified as a protein product of a putative oncogene
Actions by actin: reciprocal regulation of cortactin activity by tyrosine kinases and F-actin.
Gunst, Susan J
The Biochemical Journal, 380, e7-e8 (2004)
J N Lavoie et al.
The Journal of cell biology, 150(5), 1037-1056 (2000-09-07)
The adenoviral early region 4 open reading frame 4 (E4orf4) death factor induces p53-independent apoptosis in many cell types and appears to kill selectively transformed cells. Here we show that expression of E4orf4 in transformed epithelial cells results in early
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