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Merck
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Key Documents

14-309

Sigma-Aldrich

PCAF Protein, Active, 50 µg

PCAF recombinant GST fusion protein, for use in Histone Acetyltransferase Assays. (HAT).

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

重組細胞

expressed in E. coli

品質等級

100

分子量

Mw 79 kDa

製造商／商標名

Upstate®

技術

activity assay: suitable (histone acetyltransferase (HAT))

NCBI登錄號

NM_003884.3

UniProt登錄號

Q92831

運輸包裝

dry ice

一般說明

Product Source: expressed in E. Coli corresponding to amino acids 352-832

品質

routinely evaluated by acetylation of core histones in vitro

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

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Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3.
Jae-Hwan Lim,Katherine L West,Yaffa Rubinstein,Michael Bergel,Yuri V Postnikov,Michael Bustin
The Embo Journal null
Prabhat Kumar Purbey et al.
Molecular and cellular biology, 29(5), 1321-1337 (2008-12-24)
Special AT-rich binding protein 1 (SATB1) acts as a global regulator of gene expression by recruiting various corepressor or coactivator complexes, thereby establishing a unique chromatin structure at its genomic targets in a context-dependent manner. Although SATB1 acts predominantly as
Giosalba Burgio et al.
Journal of enzyme inhibition and medicinal chemistry, 31(sup3), 75-82 (2016-07-09)
Histones and polyamines are important determinants of the chromatin structure. Histones form the core of nucleosome particles and their modification by acetylation of N-terminal tails is involved in chromatin structural changes and transcriptional regulation. Polyamines, including spermidine, are also targets
R L Schiltz et al.
The Journal of biological chemistry, 274(3), 1189-1192 (1999-01-09)
A number of transcriptional coactivators possess intrinsic histone acetylase activity, providing a direct link between hyperacetylated chromatin and transcriptional activation. We have determined the core histone residues acetylated in vitro by recombinant p300 and PCAF within mononucleosomes. p300 specifically acetylates
Zhaohua Lu et al.
Planta medica, 72(2), 151-155 (2006-02-24)
A recombinant single chain variable-fragment (scFv) antibody against paeoniflorin (PF) was produced using the hybridoma cell line C31B9. Variable regions of heavy (V (H)) and light (V (L)) chain antibody genes were directly cloned from cDNA resources of hybridoma C31B9
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