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描述
shipped with cooling packs
產品線
Cellvento®
形狀
dry powder
環保替代產品特色
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
技術
cell culture | mammalian: suitable
環保替代類別
儲存溫度
2-8°C
一般說明
Cellvento® ModiFeed Sial+ COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously maximizing sialylation on the protein of interest. It is recommended combination with the production media Cellvento® 4CHO and EX-CELL® Advanced CHO or other production media.
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應用
Control of protein glycosylation, such as sialylation, while maximizing productivity is key for successful therapeutic protein development and production. N-glycoslyations of IgG Fc, particularly sialylation, has been reported to exert significant anti-inflammatory effects. High sialylation levels can help to increase stability, safety, and efficacy of the protein of interest. Cellvento® ModiFeed Sial+ COMP was developed to increase sialylation while maintaining or improving titer in CHO fed-batch processes
特點和優勢
- Reduced complexity in fed-batch process
- Complete feed maximizing galactosylation
- Highly concentrated to reduce required feed volume
- Compacted format for conventient handling
- Higher liquid feed stability at room temperature
數量
Formulated to contain 155.8 grams of powder per liter of feed.
法律資訊
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
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