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Merck
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Key Documents

06-559

Sigma-Aldrich

Anti-Pyk2 Antibody

Upstate®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human, mouse

製造商/商標名

Upstate®

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... PTK2B(2185)

特異性

Recognizes Pyk2, and its degradation products; does not cross-react with FAK.

免疫原

GST-fusion protein containing amino acids 726-863 of human Pyk2

應用

Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling
This Anti-Pyk2 Antibody is validated for use in IC, IP, WB for the detection of Pyk2.

品質

routinely evaluated by immunoblot on mouse brain cytosolic RIPA lysates

標靶描述

125 kDa

外觀

Protein A purified
Format: Purified
Protein A Purified immunoglobulin in 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Mouse brain cytosolic RIPA lysates

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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S Eguchi et al.
Hypertension (Dallas, Tex. : 1979), 33(1 Pt 2), 201-206 (1999-02-04)
-PYK2, a recently identified Ca2+-sensitive tyrosine kinase, has been implicated in extracellular signal-regulated kinase (ERK) activation via several G protein-coupled receptors. We have reported that angiotensin II (Ang II) induces Ca2+-dependent transactivation of the epidermal growth factor receptor (EGFR) which
Effects of the integrin-linked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck.
Younes, MN; Yigitbasi, OG; Yazici, YD; Jasser, SA; Bucana, CD; El-Naggar, AK; Mills, GB; Myers, JN
Archives of Otolaryngology--Head & Neck Surgery null
Rongfang Wei et al.
Cancer communications (London, England), 42(11), 1185-1206 (2022-08-31)
Multiple myeloma (MM) is the second most common hematological malignancy. An overwhelming majority of patients with MM progress to serious osteolytic bone disease. Aminoacyl-tRNA synthetase-interacting multifunctional protein 1 (AIMP1) participates in several steps during cancer development and osteoclast differentiation. This
p21 as a transcriptional co-repressor of S-phase and mitotic control genes.
Ferrandiz, N; Caraballo, JM; Garcia-Gutierrez, L; Devgan, V; Rodriguez-Paredes, M; Lafita et al.
Testing null
Mad3 negatively regulates B cell differentiation in the spleen by inducing Id2 expression.
Gore, Y; Lantner, F; Hart, G; Shachar, I
Molecular Biology of the Cell null

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