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Key Documents

05-919

Sigma-Aldrich

抗-T 细胞受体抗体(克隆 C305)

culture supernatant, clone C305, Upstate®

别名:

T-Cell receptor antibody

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

C305, monoclonal

物種活性

human

製造商/商標名

Upstate®

技術

immunoprecipitation (IP): suitable
multiplexing: suitable

同型

IgM

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... TRDD3(28523)

特異性

Jurkat T细胞受体

免疫原

Jurkat T细胞

應用

抗-T细胞受体抗体(克隆C305)可检测T细胞受体的水平 &已有相关文献发表&经过验证可用于Mplex & IP。
研究子类别
免疫球蛋白 & 免疫学
研究类别
炎症 & 免疫学

品質

常规用于生物测定,用于激活Jurkat细胞中的T细胞受体信号级联

外觀

浓缩的培养上清液。

儲存和穩定性

自运送之日起在-20°C下稳定保存2年

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Identification of the minimal tyrosine residues required for linker for activation of T cell function.
Lin, J and Weiss, A
The Journal of Biological Chemistry, 276, 29588-29595 (2001)
Nadia Martinez-Martin et al.
Nature communications, 7, 11473-11473 (2016-05-06)
Viruses encode secreted and cell-surface expressed proteins essential to modulate host immune defenses and establish productive infections. However, to date there has been no systematic study of the extracellular interactome of any human virus. Here we utilize the E3 proteins
Pussadee Paensuwan et al.
Journal of immunology (Baltimore, Md. : 1950), 196(1), 448-458 (2015-11-22)
Ligand binding to the TCR causes a conformational change at the CD3 subunits to expose the CD3ε cytoplasmic proline-rich sequence (PRS). It was suggested that the PRS is important for TCR signaling and T cell activation. It has been shown
Joseph Lin et al.
The Journal of cell biology, 162(4), 673-682 (2003-08-13)
CD148 is a receptor-like protein tyrosine phosphatase up-regulated on T cells after T cell receptor (TCR) stimulation. To examine the physiologic role of CD148 in TCR signaling, we used an inducible CD148-expressing Jurkat T cell clone. Expression of CD148 inhibits
A Weiss et al.
The Journal of experimental medicine, 160(5), 1284-1299 (1984-11-01)
The association between T3 and the T cell antigen receptor was examined using the T3 bearing T cell leukemic line Jurkat. A monoclonal antibody, C305, was produced, which reacted with idiotypic-like determinants expressed on Jurkat. The molecule with which this

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