生物源
rabbit
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
monoclonal
物種活性
human, mouse
製造商／商標名
Upstate®
技術
immunoprecipitation (IP): suitable
western blot: suitable
同型
IgG
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... GSK3A(2931)
特異性
GSK3 alpha and beta
Predicted to cross-react with rat based on sequence homology
免疫原
N-terminal 6His-tagged recombinant full length human GSK3β
應用
Anti-GSK3α/β Antibody is an antibody against GSK3α/β for use in IP & WB.
品質
routinely evaluated by immunoblot on lysates from HEK293 cells
標靶描述
Mr 46kDa (beta) and 51kDa (alpha)
外觀
Format: Purified
分析報告
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Yasuhiro Nishino et al.
Circulation research, 103(3), 307-314 (2008-06-28)
The inactivation of glycogen synthase kinase-3beta (GSK-3beta) is proposed as the event integrating protective pathways initiated by preconditioning and other interventions. The inactivation of GSK-3 is thought to decrease the probability of opening of the mitochondrial permeability transition pore. The
Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication.
Chuluunbaatar, U; Roller, R; Feldman, ME; Brown, S; Shokat, KM; Mohr, I
Genes & Development null
Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes.
Jope, Richard S
Trends in Pharmacological Sciences, 24, 441-443 (2003)
GSK-3: tricks of the trade for a multi-tasking kinase.
Doble, Bradley W and Woodgett, James R
Journal of Cell Science, 116, 1175-1186 (2003)
Jen Q Pan et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 36(7), 1397-1411 (2011-03-11)
Bipolar disorder (BP) is a debilitating psychiatric disorder, affecting ∼2% of the worldwide population, for which the etiological basis, pathogenesis, and neurocircuitry remain poorly understood. Individuals with BP suffer from recurrent episodes of mania and depression, which are commonly treated
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