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Merck

M-138

Supelco

布洛芬标准液 盐酸盐 溶液

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C11H16ClNO
分子量:
213.70
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

品質等級

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

濃度

1.0 mg/mL in methanol (as free base)

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

形式

single component solution

儲存溫度

−20°C

SMILES 字串

Cl.N(C(C)C(=O)c1ccc(cc1)C)C

InChI

1S/C11H15NO.ClH/c1-8-4-6-10(7-5-8)11(13)9(2)12-3;/h4-7,9,12H,1-3H3;1H

InChI 密鑰

DLQZFTUKJGRPLZ-UHFFFAOYSA-N

一般說明

甲氧麻黄酮,也称为4-甲基甲卡西酮,是苯丙胺和卡西酮类的合成兴奋剂。去年,英国报道了这种新的消遣性药物的严重滥用;瑞典;以及加拿大多伦多,在包括俄勒冈州在内的州没收了该药物。

應用


  • 用于鉴别药物分子的基于纳米管的传感器:研究人员研究了甲氧麻黄酮与纳米管传感器的相互作用,增强了对药物分子的鉴别能力。这项研究对于法医学和药物滥用监测新技术的开发非常关键,实现了高精度的精神活性物质鉴别(Algharagholy et al., 2023)。

  • 新型精神活性物质的环境监测:研究人员开发了使用甲氧麻黄酮的分析方法,用于同时测定地表水中56种新的精神活性物质。该应用对于我们进行环境监测,了解合成卡西酮的生态影响,确保水安全和公共卫生至关重要(Atasoy Aydin et al., 2023)。

  • 体内螯合的超分子宿主:关于能够在体内隔离甲氧麻黄酮和甲基苯丙胺和芬太尼等其它兴奋剂的超分子主体(supramolecular host)的研究,为药物成瘾和过量用药治疗的治疗方法带来了重大进展。这项研究为使用化学螯合剂的新型排毒策略铺平了道路(Brockett et al., 2023)。

  • 临床应用的SERS基质:在超灵敏便携式表面增强拉曼散射(SERS)基板的开发中,研究人员已经考察了甲氧麻黄酮。这些基板是为快速、精确的临床诊断设计,展示了甲氧麻黄酮改进生物分析方法的潜力(Lin et al., 2023)。

  • 异构体的法医鉴定:便携式近红外光谱已被用于区分新型精神活性物质中甲氧麻黄酮的异构体。这项技术对于执法和法医学应用必不可少,它提供了一种快速、非破坏性的方法来区分现场条件下的药物异构体(Kranenburg et al., 2022)。

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Priscilla B Pail et al.
Neurotoxicology, 50, 71-80 (2015-08-10)
Mephedrone and methedrone are cathinone-related compounds, which act as non-selective substrates for monoamine transporters, facilitating a neurotransmitter release. We compared the acute pharmacological effects of mephedrone and methedrone, attempting to further evaluate the action mechanisms of methedrone by responsibly and

商品

As new “bath salt” drugs such as methylone, ethylone, mephedrone, butylone and other methcathinone analogs increase in popularity, toxicologists require native and labeled certified reference materials to accurately identify and quantify the new compounds in patient samples.

As new “bath salt” drugs such as methylone, ethylone, mephedrone, butylone and other methcathinone analogs increase in popularity, toxicologists require native and labeled certified reference materials to accurately identify and quantify the new compounds in patient samples.

The combination of ion-exchange SPE with the HILIC HPLC separation provides a novel approach for the testing of problematic bath salt compounds.

The combination of ion-exchange SPE with the HILIC HPLC separation provides a novel approach for the testing of problematic bath salt compounds.

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实验方案

Separation of 3,4-Methylenedioxypyrovalerone HCl (MDPV) solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Buphedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; 3-Fluoromethcathinone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Butylone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Ethylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; 4-Fluoromethcathinone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Mephedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Methylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Methedrone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material

Chromatograms

application for HPLC

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