A-006

6-乙酰吗啡-D_{3标准液 CRM 溶液}

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• 别名: 6-乙酰吗啡-N-甲基-d₃ 溶液
• 经验公式（希尔记法）: C₁₉D₃H₁₈NO₄
• CAS号: 136765-25-8
• 分子量: 330.39
• EC號碼: 200-835-2
• MDL號碼: MFCD00673257
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329770568
• NACRES: NA.24

属性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: SNAP-N-SPIKE^®. SNAP-N-SHOOT^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 100 μg/mL in acetonitrile
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 質量偏移: M+3
• 儲存溫度: −20°C
• SMILES 字串: [2H]C([2H])([2H])N1CC[C@]23C4Oc5c(O)ccc(CC1C2C=C[C@@H]4OC(C)=O)c35
• InChI: 1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1/i2D3
• InChI 密鑰: JJGYGPZNTOPXGV-VALGNVEGSA-N

说明

一般說明

适用于临床毒理学、法医学分析、尿液药物检测、疼痛处方监测和同位素稀释方法的 GC/MS 或 LC/MS 检测中定量测定 6-乙酰吗啡 (6-MAM) 水平的稳定标记内标物。也被称为 6-单乙酰吗啡，6-MAM 是海洛因的活性代谢产物和海洛因使用的生物标志物。

應用

• Quantitative analysis of opiates in human fluids: A study employed 6-Acetylmorphine-d3 solution as part of a bioanalytical method using gas chromatography-triple quadrupole mass spectrometry for the precise quantification of opiates in human blood samples, highlighting its utility in forensic and clinical toxicology (Saad et al., 2019).


• Enhanced opioid metabolite detection: Research integrated 6-Acetylmorphine-d3 solution in an electrospray LC-MS method with solid-phase extraction, significantly improving the accuracy of detecting opioid metabolites in urine. This method is vital for drug monitoring and pharmacokinetic studies (Svensson et al., 2007).


• Forensic application in controlled drug programs: A study used 6-Acetylmorphine-d3 solution to establish dose-concentration relationships in hair from subjects in a controlled heroin-maintenance program, proving its essential role in forensic science for monitoring drug intake (Kintz et al., 1998).


• Drug monitoring in clinical settings: The solution was also applied in a novel assay for the determination of opioids in blood and pericardial fluid, offering a robust tool for clinical diagnostics and forensic investigations (Ferreira et al., 2020).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02,GHS07
• 訊號詞: Danger
• 危險聲明: H225,H302 + H312 + H332,H319
• 防範說明: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 35.6 °F - closed cup
• 閃點（°C）: 2 °C - closed cup