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形狀
methanol solution
包裝
pkg of 1 × 1 mL (LM4103-1EA)
製造商/商標名
Avanti Polar Lipids LM4103
濃度
~10 μg/mL (Refer to C of A for lot specific concentration. )
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=C[C@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
一般說明
7α-hydroxycholesterol is an oxysterol synthesized by the oxidation of the side chain of cholesterol. It is the precursor of bile acid.
應用
7α-hydroxycholesterol (D7) may be used:
- as a deuterated sterol standard for the extraction of lipids from cultured cells
- in liquid chromatography-high-resolution mass spectrometry method (LC-MS/HR-MS) for the quantification
- to synthesize d4-7 -hydroxy-3-oxo-4-cholestenoic acid (d4-7-HOCA)
包裝
2 mL Amber Glass Sealed Ampule (LM4103-1EA)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
49.5 °F - closed cup
閃點(°C)
9.7 °C - closed cup
Quantification of the 15 major human bile acids and their precursor 7? -hydroxy-4-cholesten-3-one in serum by liquid chromatography--tandem mass spectrometry
Journal of Chromatography. B, Biomedical Applications, 878(28), 2870-2880 (2010)
Oxysterols in the pathogenesis of major chronic diseases
Redox Biology, 1(1), 125-130 (2013)
7 ? -hydroxy-3-oxo-4-cholestenoic acid in cerebrospinal fluid reflects the integrity of the blood-brain barrier
Journal of Lipid Research, 55(2), 313-318 (2014)
Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry
Test, 432, 145-170 (2007)
Journal of chromatography. A, 1439, 82-88 (2015-11-27)
Oxysterols are important intermediates in numerous metabolic and catabolic pathways and their biological significance is also proven. The present paper describes a reliable and short liquid chromatography-high-resolution mass spectrometry method (LC-MS/HR-MS) for the quantification of 8 different oxysterols (24(S)-hydroxycholesterol, 25-hydroxycholesterol
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