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形狀
methanol solution
包裝
pkg of 1 × 1 mL (LM1600-1EA)
製造商／商標名
Avanti Research™ - A Croda Brand
濃度
~10 μg/mL (Refer to C of A for lot specific concentration. )
應用
lipidomics
metabolomics
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
O[C@](COP(O)(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCC)=O
一般說明
溶血磷脂酰胆碱（LPC）是一种极性脂质，位于氧化脂蛋白的细胞膜上。
應用
13：0溶血LPC或1-十三烷酰基-sn-甘油-3-磷酸胆碱已被用作内标：
- 从脑组织中提取脂质
- 使用改良的Bligh和Dyer方案从巨噬细胞中提取脂质
- 溶血磷脂的液相色谱/质谱分析
生化／生理作用
已知溶血磷脂酰胆碱（LPC）是一种生物活性分子，与动脉粥样硬化的进展有关，并发现病变/斑块中LPC的高浓度。在表明心血管疾病的氧化损伤的低密度脂蛋白（oxLDL）中也发现较高水平的LPC。LPC参与多种生物过程，例如血管再生，发育和髓磷脂形成。还已知它与神经元疾病和癌症有关。
包裝
2mL琥珀色玻璃密封安瓿（LM1600-1EA）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
49.5 °F - closed cup
閃點（°C）
9.7 °C - closed cup
Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
Matthew W Granger et al.
Journal of neurochemistry, 149(4), 499-517 (2018-07-25)
Changes in glycerophosphocholine metabolism are observed in Alzheimer's disease; however, it is not known whether these metabolic disruptions are linked to cognitive decline. Here, using unbiased lipidomic approaches and direct biochemical assessments, we profiled Land's cycle lipid remodeling in the
Luis Gil-de-Gómez et al.
Journal of immunology (Baltimore, Md. : 1950), 192(2), 752-762 (2013-12-18)
Phospholipase A2s generate lipid mediators that constitute an important component of the integrated response of macrophages to stimuli of the innate immune response. Because these cells contain multiple phospholipase A2 forms, the challenge is to elucidate the roles that each
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