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Merck

890820C

Avanti

18:0 DAP

Avanti Polar Lipids 890820C

别名:

1,2-distearoyl-3-dimethylammonium-propane

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About This Item

经验公式(希尔记法):
C41H81NO4
分子量:
652.09
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

liquid

包裝

pkg of 1 × 2.5 mL (890820C-25mg)

製造商/商標名

Avanti Polar Lipids 890820C

濃度

10 mg/mL (890820C-25mg)

脂質類型

transfection
cationic lipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(CN(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O

應用

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) might be used to formulate lipid nanoparticles (LNPs) and to test its efficiency of packaging mRNA into an LNP. It might also be used in the preparation of “bubble liposomes” (BLs).

生化/生理作用

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.

包裝

5 mL Clear Glass Sealed Ampule (890820C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


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Yoko Endo-Takahashi et al.
Biomaterials, 34(11), 2807-2813 (2013-01-25)
We have developed polyethyleneglycol (PEG)-modified liposomes (Bubble liposomes; BLs) that entrap ultrasound (US) contrast gas, and we have reported that the combination of BLs and US exposure was an effective tool for delivering pDNA and siRNA in vitro and in

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