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Merck

870716P

Avanti

16:0辅酶A

Avanti Research - A Croda Brand 870716P, powder

别名:

棕榈酰辅酶A铵盐

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About This Item

经验公式(希尔记法):
C37H75N10O17P3S
分子量:
1057.03
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 10 mg (870716P-10mg)
pkg of 1 × 25 mg (870716P-25mg)
pkg of 1 × 5 mg (870716P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 870716P

應用

lipidomics

脂質類型

coenzymes

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]

InChI

1S/C37H66N7O17P3S.3H3N/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44;;;/h24-26,30-32,36,47-48H,4-23H2,1-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52);3*1H3/t26-,30?,31+,32+,36-;;;/m1.../s1

InChI 密鑰

VJXJWGKNGIGUQX-AUCFWDBISA-N

一般說明

16:0辅酶A,又称为棕榈酰辅酶A,是含量最为丰富的酰基-CoA,是β-氧化的第一轮产物。它可作为反应底物,在蛋白酰基转移酶催化下通过棕榈酰化反应将棕榈酰基转移到靶标蛋白的游离巯基上。

應用

16:0辅酶A已用作:
  • 分枝杆菌细胞内棕榈酰-CoA质谱法定量分析的标准品
  • 蛋白体外结合实验的结合缓冲液组分
  • 丝氨酸棕榈酰基转移酶的测定底物

包裝

5 mL棕色玻璃螺旋盖小瓶 (870716P-10mg)
5 mL棕色玻璃螺旋盖小瓶 (870716P-25mg)
5 mL棕色玻璃螺旋盖小瓶 (870716P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


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Cheryl Budde et al.
Methods (San Diego, Calif.), 40(2), 143-150 (2006-10-03)
Palmitoylation enhances membrane association and plays a role in the subcellular trafficking and signaling function of proteins. Unlike other forms of protein lipidation, such as prenylation and myristoylation, palmitoylation is reversible and can therefore play a regulatory role. Enzyme activities
Matías Cabruja et al.
Applied microbiology and biotechnology, 100(16), 7239-7248 (2016-06-09)
Acyl-CoAs are crucial compounds involved in essential metabolic pathways such as the Krebs cycle and lipid, carbohydrate, and amino acid metabolisms, and they are also key signal molecules involved in the transcriptional regulation of lipid biosynthesis in many organisms. In
Oshrit Ben-David et al.
The Journal of biological chemistry, 286(34), 30022-30033 (2011-06-28)
Sphingolipids (SLs) act as signaling molecules and as structural components in both neuronal cells and myelin. We now characterize the biochemical, histological, and behavioral abnormalities in the brain of a mouse lacking very long acyl (C22-C24) chain SLs. This mouse
Anke Penno et al.
The Journal of biological chemistry, 285(15), 11178-11187 (2010-01-26)
HSAN1 is an inherited neuropathy found to be associated with several missense mutations in the SPTLC1 subunit of serine palmitoyltransferase (SPT). SPT catalyzes the condensation of serine and palmitoyl-CoA, the initial step in the de novo synthesis of sphingolipids. Here
Taras Y Nazarko et al.
The Journal of cell biology, 204(4), 541-557 (2014-02-19)
Autophagy is a membrane trafficking pathway that sequesters proteins and organelles into autophagosomes. The selectivity of this pathway is determined by autophagy receptors, such as the Pichia pastoris autophagy-related protein 30 (Atg30), which controls the selective autophagy of peroxisomes (pexophagy)

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