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形狀
powder
包裝
pkg of 1 × 5 mg (860510P-5mg)
製造商/商標名
Avanti Research™ - A Croda Brand 860510P
脂質類型
sphingolipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
OC[C@]([H])(NC(CCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C28H55NO3/c1-3-5-7-9-11-12-13-14-15-16-18-19-21-23-27(31)26(25-30)29-28(32)24-22-20-17-10-8-6-4-2/h21,23,26-27,30-31H,3-20,22,24-25H2,1-2H3,(H,29,32)/b23-21+/t26-,27+/m0/s1
InChI 密鑰
FDWVAQFAMZLCAX-NBNLIBPQSA-N
一般說明
C10 Ceramide (d18:1/10:0) is a synthetic ceramide containing sphingosine with decanoic acid. It has a short acyl chain length than sphingosine acyl chain.
應用
C10 Ceramide (d18:1/10:0) or N-decanoyl-D-erythro-sphingosine has been used:
- as an internal standard in galactocerebrosidase (GALC) assay
- to study its role on the physical properties of edible organogels and on their ability to induce cell death of various cancer cell lines
- to study its mixing behavior with other ceramides having the same sphingosine base but varying N-linked acyl chain length
生化/生理作用
Ceramides modulate stress responses and inflammation. It also controls cell differentiation, proliferation and apoptosis.
包裝
5 mL Amber Glass Screw Cap Vial (860510P-5mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Chemistry and physics of lipids, 194, 110-116 (2015-09-27)
A ceramide commonly found in mammalian cells, C16-ceramide (N-palmitoyl-d-erythro-sphingosine), is capable of forming large, protein-permeable channels in the mitochondrial outer membrane (MOM). However, C16-ceramide is unable to permeabilize the plasma membrane of erythrocytes. This specificity is unexpected considering that ceramide
The Journal of investigative dermatology, 133(3), 668-676 (2012-10-26)
The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and giving rise to epidermal permeability barrier (EPB). EPB defects have an important role in the pathophysiology of skin diseases
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