860463P

N-C16-desoxymethylsphinganine

Avanti Polar Lipids 860463P, powder

• 别名: N-palmitoyl-1-desoxymethylsphinganine (m17:0/16:0)
• 经验公式（希尔记法）: C₃₃H₆₇NO₂
• CAS号: 1246298-42-9
• 分子量: 509.89
• 分類程式碼代碼: 12352211
• NACRES: NA.25

属性

• 形狀: powder
• 包裝: pkg of 1 × 1 mg (860463P-1mg); pkg of 1 × 5 mg (860463P-5mg)
• 製造商／商標名: Avanti Polar Lipids 860463P
• 脂質類型: sphingolipids; bioactive lipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: [H][C@](CCCCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCCCC)=O

说明

一般說明

N-C16-desoxymethylsphinganine is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of N-acylsphinganines (dihydroceramides) levels and accumulation of sphinganine. Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.

生化／生理作用

Dihydroceramides are also used for dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.

包裝

5 mL Amber Glass Screw Cap Vial (860463P-1mg)

5 mL Amber Glass Screw Cap Vial (860463P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3