860461P

N-C12-desoxymethylsphinganine

N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder

• 别名: N-dodecanoyl-1-desoxymethylsphinganine (m17:0/12:0); N-C12-1-desoxyMeDHCer; 110959
• 经验公式（希尔记法）: C₂₉H₅₉NO₂
• CAS号: 1246298-41-8
• 分子量: 453.78
• 分類程式碼代碼: 12352211
• NACRES: NA.25

属性

• 化驗: >99% (TLC)
• 形狀: powder
• 包裝: pkg of 1 × 1 mg (860461P-1mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 860461P
• 脂質類型: sphingolipids; bioactive lipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C

说明

一般說明

Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.

N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.

生化／生理作用

Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.

包裝

5 mL Amber Glass Screw Cap Vial (860461P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3