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描述
Sphingomyelin (Egg, Chicken)
化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 1 g (860061P-1g)
pkg of 1 × 200 mg (860061P-200mg)
pkg of 1 × 25 mg (860061P-25mg)
製造商／商標名
Avanti Research™ - A Croda Brand
脂質類型
sphingolipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O
InChI
1S/C39H79N2O6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-38(42)37(36-47-48(44,45)46-35-34-41(3,4)5)40-39(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h30,32,37-38,42H,6-29,31,33-36H2,1-5H3,(H-,40,43,44,45)/b32-30+/t37-,38+/m0/s1
InChI 密鑰
RWKUXQNLWDTSLO-GWQJGLRPSA-N
一般說明
作为细胞膜的主要成分，鞘磷脂在神经细胞（髓鞘）膜和红细胞膜中的浓度特别高。以前认为，它是因鞘氨醇碱基的2-酰胺基、3-羟基和4,5-反式双键介导的分子间相互作用而具有与磷脂酰胆碱功能相似的纯结构作用。但是，现在人们认识到，鞘磷脂对胆固醇具有高亲和力，这两种脂质在液体无序相中紧密堆积成液体有序结构域，形成脂质筏。这些膜微结构域被认为是调节蛋白质定位和相互作用的信号转导平台。但是，鞘磷脂不仅是会影响信号传导的脂质筏成分，它还是神经酰胺和其他鞘脂代谢（包括鞘磷脂循环或鞘脂网络）产物的前体。
鞘磷脂和相关脂质
鞘磷脂和相关脂质
應用
蛋黄SM可用于制备鞘磷脂（SM）标准溶液。还可用于制备脂质体。
包裝
20 mL透明玻璃螺旋盖样品瓶（860061P-1g）
5 mL棕色玻璃螺旋盖样品瓶（860061P-200mg）
5 mL棕色玻璃螺旋盖样品瓶（860061P-25mg）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Protocols for Enzymatic Fluorometric Assays to Quantify Phospholipid Classes
Morita S, et al.
International Journal of Molecular Sciences, 21(3), 1032-1032 (2020)
Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography
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Journal of Virology, 86(22), 12129-12137 (2012)
Maia Kinnebrew et al.
eLife, 8 (2019-10-29)
Previously we proposed that transmission of the hedgehog signal across the plasma membrane by Smoothened is triggered by its interaction with cholesterol (Luchetti et al., 2016). But how is cholesterol, an abundant lipid, regulated tightly enough to control a signaling
Takaaki Matsufuji et al.
Langmuir : the ACS journal of surfaces and colloids, 34(1), 465-471 (2017-12-13)
Ceramide is a bioactive lipid with important roles in several biological processes including cell proliferation and apoptosis. Although 3-ketoceramides that contain a keto group in place of the 3-OH group of ceramide occur naturally, ceramide derivatives oxidized at the primary
Yuanqing Ma et al.
Biophysical journal, 115(8), 1498-1508 (2018-10-03)
Membrane viscosity and hydration levels characterize the biophysical properties of biological membranes and are reflected in the rate and extent of solvent relaxation, respectively, of environmentally sensitive fluorophores such as Laurdan. Here, we first developed a method for a time-resolved
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