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化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 10 mg (857503P-10MG)
pkg of 1 × 5 mg (857503P-5MG)
製造商／商標名
Avanti Research™ - A Croda Brand (857503P)
脂質類型
phospholipids
bacterial lipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCC[C@H](C)CC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
一般說明
Phosphatidylcholine (PC) is one of the major zwitterionic glycerophospholipids of the eukaryotic membranes. PC is synthesized in higher eukaryotes by triple methylation of phosphatidylethanolamine and by the cytidine diphosphate (CDP)-choline pathway. PC is a cylindrical shaped molecule.
生化／生理作用
Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. Biosynthesis of PC is essential for normal very low density lipoprotein secretion from hepatocytes. PC is the dominant phospholipid present in cancer and non-neoplastic tissues.
包裝
5 mL Amber Glass Screw Cap Vial (857503P-5MG and 857503P-10MG)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Nobuya Kurabe et al.
Cancer science, 104(10), 1295-1302 (2013-07-03)
The identification of cancer biomarkers is critical for target-linked cancer therapy. The overall level of phosphatidylcholine (PC) is elevated in colorectal cancer (CRC). To investigate which species of PC is overexpressed in colorectal cancer, an imaging mass spectrometry was performed
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
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