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化驗
>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
形狀
powder
包裝
pkg of 1 × 200 mg (855475P-200mg)
pkg of 1 × 25 mg (855475P-25mg)
pkg of 1 × 500 mg (855475P-500mg)
製造商／商標名
Avanti Research™ - A Croda Brand 855475P
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCC)=O
InChI
1S/C20H42NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3/t19-/m1/s1
InChI 密鑰
BWKILASWCLJPBO-LJQANCHMSA-N
一般說明
溶血磷脂酰胆碱（LPC）是一种在病理反应中分泌的具有生物活性的促炎脂质。它在其极性头部有一个胆碱基团。溶血磷脂酰胆碱（Lyso-PC）是血浆、血管组织和脂蛋白的成分。
應用
12:0 Lyso PC已用于研究其神经形成活性和外源性脂质的应用。
生化／生理作用
溶血磷脂酰胆碱（LPC）改变不同细胞类型的各种功能，例如内皮细胞，平滑肌细胞，单核细胞，巨噬细胞和T细胞。它与动脉硬化症和炎症性疾病有关。LPC激活许多第二信使，包括蛋白激酶C、细胞外信号调节激酶和蛋白酪氨酸激酶。
包裝
20 mL透明玻璃螺旋盖小瓶（855475P-500mg）
5 mL棕色玻璃螺旋盖小瓶（855475P-200mg）
5 mL棕色玻璃螺旋盖小瓶（855475P-25mg）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Inner/outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis
Fichtman B, et al.
Molecular Biology of the Cell, 21(23) (2010)
Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor
Ikeno Y, et al.
Test, 280(30) (2005)
Boris Fichtman et al.
Molecular biology of the cell, 21(23), 4197-4211 (2010-10-12)
Nuclear pore complexes (NPCs) are large proteinaceous channels embedded in double nuclear membranes, which carry out nucleocytoplasmic exchange. The mechanism of nuclear pore assembly involves a unique challenge, as it requires creation of a long-lived membrane-lined channel connecting the inner
Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells
Wong JT, et al.
Test, 273(12), 6830-6836 (1998)
Yutaka Ikeno et al.
The Journal of biological chemistry, 280(30), 28044-28052 (2005-06-02)
We previously demonstrated that secretory phospholipase A2 (sPLA2) and lysophosphatidylcholine (LPC) exhibit neurotrophin-like neuritogenic activity in the rat pheochromocytoma cell line PC12. In this study, we further analyzed the mechanism whereby sPLA2 displays neurite-inducing activity. Exogenously added mammalian group X
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