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描述
1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform
化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 5 mL (852758C-10mg)
pkg of 1 × 5 mL (852758C-5mg)
製造商／商標名
Avanti Research™ - A Croda Brand
濃度
1 mg/mL (852758C-5mg)
2 mg/mL (852758C-10mg)
脂質類型
phospholipids
cardiolipins
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O
一般說明
Phosphatidylethanolamine is an aminophospholipid. It is present in eukaryotic and prokaryotic cells. Phosphatidylethanolamine is one of the most abundant glycerophospholipids in the biological membranes. It is found in nervous tissue.
應用
C18(Plasm)-18:1 PE has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS).
生化／生理作用
Phosphatidylethanolamine forms pure lipid structures, which regulate membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a major role in autophagy, cell division and protein folding. It functions as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine acts as an intermediate for the synthesis of glycerophospholipid classes.
包裝
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852758C-10mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852758C-5mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
標靶器官
Liver,Kidney, Respiratory system
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
does not flash
閃點（°C）
does not flash
The Membranes of Cells (2016)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
Nathan R Deleault et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1938-E1946 (2012-06-20)
Prions containing misfolded prion protein (PrP(Sc)) can be formed with cofactor molecules using the technique of serial protein misfolding cyclic amplification. However, it remains unknown whether cofactors materially participate in maintaining prion conformation and infectious properties. Here we show that
Ana West et al.
The journal of physical chemistry. B, 124(5), 828-839 (2020-01-10)
Ethanolamine plasmalogen (EtnPLA) is a conical-shaped ether lipid and an essential component of neurological membranes. Low stability against oxidation limits its study in experiments. The concentration of EtnPLA in the bilayer varies depending on cell type and disease progression. Here
Geoffrey P Noble et al.
Biochemistry, 54(5), 1180-1187 (2015-01-15)
Misfolding of the prion protein (PrP) plays a central role in the pathogenesis of infectious, sporadic, and inherited prion diseases. Here we use a chemically defined prion propagation system to study misfolding of the pathogenic PrP mutant D177N in vitro.
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