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Merck

850758P

Avanti

18:0-18:1 PE

1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine, powder

别名:

1-十八烷酰基-2-(9Z-十八烯酰基)-sn-甘油-3-磷酸乙醇胺;SOPE;PE(18:0/18:1(9Z))

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About This Item

经验公式(希尔记法):
C41H80NO8P
CAS号:
分子量:
746.05
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 2 × 100 mg (850758P-200mg)
pkg of 1 × 25 mg (850758P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 850758P

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O

InChI

1S/C21H14Cl2N2O2/c1-12-8-9-18-17(10-12)25-21(27-18)13-4-2-5-14(11-13)24-20(26)15-6-3-7-16(22)19(15)23/h2-11H,1H3,(H,24,26)

InChI 密鑰

GKFNHDBVWFEZCJ-UHFFFAOYSA-N

一般說明

磷脂酰乙醇胺(PE)是一种甘油磷脂。

應用

1-硬脂酰基-2-油酰基-sn-甘油-3-磷酸乙醇胺(18:0-18:1 Pe)可用于:
  • 作为单分子膜域形成和鉴定的组分
  • 合成混合酰基链7-硝基苯-2-氧杂-1,3-二氮唑-4-基-二酰基-sn-甘油-3-磷酸乙醇胺(N-NBD-PE)和(N-丽丝胺罗丹明B磺酰基)-二酰基-sn-甘油-3-磷酸乙醇胺(N-Rh-PE)探针
  • 制备脂质体

生化/生理作用

磷脂酰乙醇胺(PE)充当脂质伴侣。已知它参与自噬的启动。

包裝

5 mL透明玻璃密封安瓿(850758P-200mg)
5 mL透明玻璃密封安瓿(850758P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


分析证书(COA)

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W Stillwell et al.
Chemistry and physics of lipids, 104(2), 113-132 (2000-02-11)
A major problem in defining biological membrane structure is deducing the nature and even existence of lipid microdomains. Lipid microdomains have been defined operationally as heterogeneities in the behavior of fluorescent membrane probes, particularly the fluorescence resonance energy transfer (FRET)
Federica Gibellini et al.
IUBMB life, 62(6), 414-428 (2010-05-27)
The glycerophospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE) account for greater than 50% of the total phospholipid species in eukaryotic membranes and thus play major roles in the structure and function of those membranes. In most eukaryotic cells, PC and PE
Jone Garate et al.
Journal of the American Society for Mass Spectrometry, 31(3), 517-526 (2020-03-05)
Imaging mass spectrometry (IMS) is becoming an essential technique in lipidomics. Still, many questions remain open, precluding it from achieving its full potential. Among them, identification of species directly from the tissue is of paramount importance. However, it is not
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
Marco M Manni et al.
eLife, 7 (2018-03-16)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of

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