跳转至内容
Merck
所有图片(2)

Key Documents

View All Documentation

850459C

Avanti

16:0-20:4 PC

Avanti Research™ - A Croda Brand

别名:

1-hexadecanoyl-2--(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; PAPC; PC(16:0/20:4(5Z,8Z,11Z,14Z))

登录查看公司和协议定价
所有图片(2)

About This Item

经验公式（希尔记法）:
C44H80NO8P
CAS号:
35418-58-7
分子量:
782.08
分類程式碼代碼:
51191904
NACRES:
NA.25

描述

1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine, chloroform

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (850459C-25mg)
pkg of 2 × 4 mL (850459C-200mg)

製造商／商標名

Avanti Research™ - A Croda Brand

濃度

10 mg/mL (850459C-25mg)
25 mg/mL (850459C-200mg)

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

InChI

1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-21-22-23-25-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-24-19-17-15-13-11-9-7-2/h14,16,20-21,23,25,28,30,42H,6-13,15,17-19,22,24,26-27,29,31-41H2,1-5H3/b16-14-,21-20-,25-23-,30-28-/t42-/m1/s1

InChI 密鑰

PUDHBQQGURLBGJ-IVFHWKNFSA-N

相关类别

一般說明

Phosphatidylcholine (PC) is one of the major glycerophospholipids of the eukaryotic membranes. PC is zwitterionic. PC is synthesized via two pathways in higher eukaryotes like the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway.

應用

16:0-20:4 PC is suitable for use:
  • in the preparation of auto-oxidised phospholipid for electrospray ionisation mass spectroscopic (ESI-MS) analysis
  • in liposome preparation for the treatment of organoid
  • as antigen in enzyme linked immunosorbent assay (ELISA) for the detection of autoantibodies to phospholipids

生化／生理作用

Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.

包裝

5 mL Clear Glass Sealed Ampule (850459C-200mg)
5 mL Clear Glass Sealed Ampule (850459C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

也與該產品經常一起購買

产品编号
说明
价格

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

does not flash

閃點（°C）

does not flash

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

William W Turner et al.
Journal of medicinal chemistry, 55(18), 8178-8182 (2012-09-01)
Macrophage scavenger receptors appear to play a major role in the clearance of oxidized phospholipid (OxPL) products. Discrete peptide-phospholipid conjugates with the phosphatidylcholine headgroup have been shown to exhibit binding affinity for these receptors. We report the preparation of a
Mohamad Navab et al.
Circulation, 109(25), 3215-3220 (2004-06-16)
These studies were designed to determine the mechanism of action of an oral apolipoprotein (apo) A-I mimetic peptide, D-4F, which previously was shown to dramatically reduce atherosclerosis in mice. Twenty minutes after 500 microg of D-4F was given orally to
Autoantibodies to oxidized low density lipoprotein in relation with coronary artery disease
Soto Y, et al.
Human Antibodies, 18(3), 109-117 (2009)
Stefan Uderhardt et al.
The Journal of experimental medicine, 214(7), 2121-2138 (2017-06-02)
Blood coagulation is essential for physiological hemostasis but simultaneously contributes to thrombotic disease. However, molecular and cellular events controlling initiation and propagation of coagulation are still incompletely understood. In this study, we demonstrate an unexpected role of eosinophils during plasmatic
Benjamin J Ansell et al.
Circulation, 108(22), 2751-2756 (2003-11-26)
The inflammatory/antiinflammatory properties of HDL were compared with HDL cholesterol in 2 groups of patients and in age- and sex-matched control subjects. Group 1 consisted of 26 patients not yet taking a statin who presented with coronary heart disease (CHD)
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门