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Merck

850184P

Avanti

08:0 PI(3,5)P2

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt), powder

别名:

PIP2[3′,5′](8:0/8:0); 110664

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About This Item

经验公式(希尔记法):
C25H58N3O19P3
分子量:
797.66
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 100 μg (with stopper and crimp cap (850184P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850184P-500ug))

製造商/商標名

Avanti Research - A Croda Brand 850184P

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]

一般說明

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is the least found phosphoinositides (PIs) and it accounts for approximately 0.05 to 0.1% of total cellular PI.

生化/生理作用

Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) plays a key role in the embryonic development. It is very essential at postnatal stages. It is capable of activating ion channels on endosomes and lysosomes.

包裝

2 mL Amber Serum Vial with Stopper and Crimp Cap (850184P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850184P-500ug)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


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Bong-Kwan Han et al.
The Journal of biological chemistry, 288(28), 20633-20645 (2013-06-05)
Glucose/carbon metabolism is a fundamental cellular process in living cells. In response to varying environments, eukaryotic cells reprogram their glucose/carbon metabolism between aerobic or anaerobic glycolysis, oxidative phosphorylation, and/or gluconeogenesis. The distinct type of glucose/carbon metabolism that a cell carries
Gerald R V Hammond et al.
Science (New York, N.Y.), 337(6095), 727-730 (2012-06-23)
The quantitatively minor phospholipid phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P(2)] fulfills many cellular functions in the plasma membrane (PM), whereas its synthetic precursor, phosphatidylinositol 4-phosphate (PI4P), has no assigned PM roles apart from PI(4,5)P(2) synthesis. We used a combination of pharmacological and chemical

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