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Merck

840875C

Avanti

二油酰磷脂酸(18:1 PA)

Avanti Research - A Croda Brand

别名:

1,2-二-(9Z-十八烯酰)-sn-甘油-3-磷酸(钠盐);DOPA;PA (18:1 (9Z)/18:1 (9Z))

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About This Item

经验公式(希尔记法):
C39H72O8PNa
分子量:
722.95
分類程式碼代碼:
51191904
NACRES:
NA.25

描述

1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt), chloroform solution

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (840875C-25mg)
pkg of 2 × 20 mL (840875C-1g)
pkg of 2 × 4 mL (840875C-200mg)
pkg of 5 × 4 mL (840875C-500mg)

製造商/商標名

Avanti Research - A Croda Brand

濃度

10 mg/mL (840875C-25mg)
25 mg/mL (840875C-1g)
25 mg/mL (840875C-200mg)
25 mg/mL (840875C-500mg)

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

InChI

1S/C39H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,37H,3-16,21-36H2,1-2H3,(H2,42,43,44);/b19-17-,20-18-;/t37-;/m1./s1

InChI 密鑰

KHDHADSEKGCPKW-ZBFGHDQJSA-N

一般說明

二油酰磷脂酸(18:1 PA或1,2-二油酰-sn-甘油-3-磷酸钠盐)是以磷脂酸基团为骨架的修饰脂质的钠盐。

應用

二油酰磷脂酸(18:1 PA或1,2-二油酰-sn-甘油-3-磷酸钠盐)已用于:
  • 作为磷脂酸(PA)薄层色谱(TLC)分析的合成标准品,在碘染色后确定磷脂酸位置
  • 作为脂质标准品,用于优化液相色谱−质谱 (LC-MS)分析条件
  • 作为磷脂放射性标记分析的脂质标准品

生化/生理作用

磷脂酸(PA)起脂质信使作用。它在雷帕霉素(mTOR)信号转导的哺乳动物靶标中起关键作用。

包裝

30 mL带螺旋盖的琥珀色窄口玻璃瓶(840875C-1g)
5 mL透明玻璃密封安瓿(840875C-200mg)
5 mL透明玻璃密封安瓿(840875C-25mg)
5 mL透明玻璃密封安瓿(840875C-500mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


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Nature communications, 10(1), 5783-5783 (2019-12-21)
The gut microbiota represents a huge community of microorganisms that play essential roles in immune modulation and homeostasis maintenance. Microbiota transplantation is an important approach to prevent and treat disease as it can inhibit pathogen colonization and positively modulate bacterial
Shireesha Sankella et al.
The Journal of biological chemistry, 289(8), 4762-4777 (2014-01-16)
In this study we examined the role of phosphatidic acid (PA) in hepatic glucose production (HGP) and development of hepatic insulin resistance in mice that lack 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2). Liver lysophosphatidic acid and PA levels were increased ∼2- and
Taylor E Miller et al.
Biology open, 6(2), 176-186 (2016-12-25)
The removal of mRNA transcript poly(A) tails by 3'→5' exonucleases is the rate-limiting step in mRNA decay in eukaryotes. Known cellular deadenylases are the CCR4-NOT and PAN complexes, and poly(A)-specific ribonuclease (PARN). The physiological roles and regulation for PARN is
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It had been known for decades that primordial follicles in mammalian ovaries are assembled with definite numbers and represent the ovarian reserve throughout the reproductive life. Intra-oocyte PI3K/mTOR pathways have been indicated to play a central role on the activation

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