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840026C

Avanti

Liver PE

Avanti Research™ - A Croda Brand 840026C

别名:

L-α-phosphatidylethanolamine (Liver, Bovine)

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About This Item

CAS号:
383907-31-1
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (840026C-25mg)
pkg of 5 × 4 mL (840026C-500mg)

製造商／商標名

Avanti Research™ - A Croda Brand 840026C

濃度

10 mg/mL (840026C-25mg)
25 mg/mL (840026C-500mg)

脂質類型

phosphoglycerides

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O

InChI

1S/C43H78NO8P/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-43(46)52-41(40-51-53(47,48)50-38-37-44)39-49-42(45)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,17,19,22,24,28,30,41H,3-10,12,14-16,18,20-21,23,25-27,29,31-40,44H2,1-2H3,(H,47,48)/b13-11-,19-17-,24-22-,30-28-/t41-/m1/s1

InChI 密鑰

ANRKEHNWXKCXDB-BHFWLYLHSA-N

相关类别

一般說明

Phosphatidylethanolamine (PE) consists of a small polar head group with fatty acid chains. It is the second most plenteous glycerophospholipid in eukaryotic cells. PE is a non-bilayer forming phospholipid. It is found abundantly in the mitochondria.

應用

Liver PE is suitable for the preparation of liposomes.

生化／生理作用

Phosphatidylethanolamine (PE) is involved in providing rigidity to the cell membrane via hexagonal phase structures, which promote tight packing of the membrane bilayer formed by phosphotidylcholine. It is also involved in the conversion of prions from the non-toxic to toxic conformation. PE also initiates the autophagosome formation by attaching covalently to the autophagy Atg8 protein.

包裝

5 mL Clear Glass Sealed Ampule (840026C-25mg)
5 mL Clear Glass Sealed Ampule (840026C-500mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

標靶器官

Liver,Kidney, Respiratory system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

does not flash

閃點（°C）

does not flash

分析证书(COA)

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Phosphatidylethanolamine metabolism in health and disease
International Review of Cell and Molecular Biology, 321, 29-88 (2016)
A novel flow cytometric assay to quantify interactions between proteins and membrane lipids
Temmerman K and Nickel W
Journal of Lipid Research, 50(6), 1245-1254 (2009)
Ethanolamine and Phosphatidylethanolamine Partners in Health and Disease
Patel D and Witt SN
Oxidative Medicine and Cellular Longevity, 2017, 29-88 (2017)
Nadezhda Y Davydova et al.
The Biochemical journal, 476(23), 3661-3685 (2019-11-22)
In this study, we investigate the ability of ethanol-inducible CYP2E1 to interact with other cytochrome P450 species and affect the metabolism of their substrates. As a model system, we used CYP2E1-enriched human liver microsomes (HLM) obtained by the incorporation of
Koen Temmerman et al.
Journal of lipid research, 50(6), 1245-1254 (2009-01-16)
A diverse set of experimental systems has been developed to probe protein-lipid interactions. These include measurements with the headgroups of membrane lipids in solution, immobilized membrane lipids, and analysis of protein binding to membrane lipids reconstituted in liposomes. Each of

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