化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 1 mg (810241P-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand 810241P
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
Phosphoethanolamine contains a phosphate group linked with the second carbon of ethanolamine.
生化／生理作用
Phosphoethanolamine (PEA) is a precursor to phosphatidylethanolamine and phosphatidylcholine, involved in the biosynthesis of cell membrane. In human body, PEA is a product of degradation of sphingosine phosphate and endocannabinoid anandamide. PEA has potential cytotoxic properties and is known to induce the caspase-independent cell death. PEA is capable of inhibiting tumor growth in vitro and in vivo in mouse models.
包裝
5 mL Amber Glass Screw Cap Vial (810241P-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Noam Pondé et al.
Ecancermedicalscience, 10, 681-681 (2016-12-03)
The use of unproven forms of therapy in cancer treatment is very common. In Brazil, the distribution by researchers to patients of an investigational agent called phophoethanolamine (PHOS) has led to a widely publicized scientific scandal. PHOS is a precursor
Ann C Kimble-Hill et al.
The journal of physical chemistry. B, 122(35), 8404-8415 (2018-06-08)
Phosphatidylinositol (PI) lipids are necessary for many cellular signaling pathways of membrane associated proteins, such as angiomotin (Amot). The Amot family regulates cellular polarity, growth, and migration. Given the low concentration of PI lipids in these membranes, it is likely
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
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