化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 1 mg (810209P-1mg)
製造商/商標名
Avanti Research™ - A Croda Brand
運輸包裝
dry ice
儲存溫度
−20°C
InChI
1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+/t25-,27+/m0/s1
InChI 密鑰
HZIRBXILQRLFIK-VPZZKNKNSA-N
一般說明
C6-NBD ceramide is a fluorescent labelled compound, known to be useful for the detection of enzymatic action. C6-NBD ceramide is preferred over radioactive compounds.
應用
C6-NBD Ceramide is suitable as a substrate for sphingomyelin synthase activity assay.
生化/生理作用
Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthases family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.
包裝
5 mL Amber Glass Screw Cap Vial (810209P-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Handbook of Glycosyltransferases and Related Genes, 5-5 (2011)
Mammalian ceramide synthases
IUBMB Life, 62(5), 347-356 (2010)
A role for ceramides, but not sphingomyelins, as antagonists of insulin signaling and mitochondrial metabolism in C2C12 myotubes
The Journal of Biological Chemistry, 291(46), 23978-23988 (2016)
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