化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 1 mL (791638C-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand
濃度
1 mg/mL (791638C-1mg)
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
15:0-18:1-d7-PE (1-十五酰基-2-油酰基(d7)-sn-丙三基-3-磷酸乙醇胺)是氘代磷脂。该脂质包括与十五烷酸和油酸相连的磷脂酰乙醇胺。油酸为氘离子提供庇护。磷脂酰乙醇胺是一种膜磷脂，在其他甘油磷脂合成中充当中间体。
这种氘标记脂质也可在多种脂质标准的配方中获得。SPLASH™ LIPIDOMIX™标准品包括与人血浆的所有主要脂质类别对应的脂质，从而实现一种简单的内标溶液适用每种样品。
應用
15:0-18:1-d7-PE (1-十五酰基-2-油酰基(d7)-sn-丙三基-3-磷酸乙醇胺)已用于：
- 作为生物样品中脂质分离的萃取溶剂组分，
- 作为液相色谱串联质谱法(LC-MS/MS)测定血清样品的内部标准品
- 作为傅立叶变换质谱(FTMS)分析中刺穿血浆样品的内部标准品
生化／生理作用
磷脂酰乙醇胺(PE)调节蛋白质折叠、蛋白质修饰、自噬和细胞分裂。PE作为糖基磷脂酰肌醇锚定蛋白(GPI-AP)合成的底物。低水平的PE可见于帕金森病，也可抑制蛋白质成熟。
包裝
2 mL棕色玻璃密封安瓿（791638C-1mg）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
产品编号
说明
价格
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
does not flash
閃點（°C）
does not flash
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
Luce Farine et al.
Scientific reports, 5, 16787-16787 (2015-11-19)
Phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are among the most abundant phospholipids in biological membranes. In many eukaryotes, the CDP-ethanolamine and CDP-choline branches of the Kennedy pathway represent major and often essential routes for the production of PE and PC, with
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