化驗
98%
折射率
n20/D 1.524 (lit.)
bp
208 °C (lit.)
mp
−8 °C (lit.)
密度
1.103 g/mL at 25 °C (lit.)
SMILES 字串
c1ccnnc1
InChI
1S/C4H4N2/c1-2-4-6-5-3-1/h1-4H
InChI 密鑰
PBMFSQRYOILNGV-UHFFFAOYSA-N
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一般說明
哒嗪是一种单碱式1,2-二嗪化合物,通常可通过1,4-二羰基与肼反应进行制备。哒嗪环存在于如克雷达嗪、吡哆醇等多种除草剂,以及如头孢唑仑、奥拉帕利、他拉唑帕利和卡达拉嗪等多种药物中。
應用
哒嗪可用于:
- 作为构建单元,用于合成可作为GSK-3抑制剂的N-苯基-4-吡唑并[1,5-b]哒嗪-3-基-嘧啶-2-胺衍生物。
- 作为合成具有重要药用价值的吡咯并[1,2-b]哒嗪衍生物的起始材料。
- 在酸性条件下制备可作为钢铁缓蚀剂的1-(6-乙氧基-6-氧代己基)哒嗪-1-溴化铵和1-(2-溴乙酰基)哒嗪溴化铵离子液体。
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
185.0 °F - closed cup
閃點(°C)
85 °C - closed cup
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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