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Merck

D34108

Sigma-Aldrich

二苄胺

97%

别名:

(N-苄氨基甲基)苯, DBA, N,N-二苄基胺, N-(苯基甲基)苯甲胺, N-苄基-1-苯基甲胺, N-苄基苄胺, 二苄胺(8CI), 联苄胺

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About This Item

线性分子式:
(C6H5CH2)2NH
CAS号:
分子量:
197.28
Beilstein:
909664
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

97%

形狀

liquid

折射率

n20/D 1.574 (lit.)

bp

300 °C (lit.)

mp

−26 °C (lit.)

密度

1.026 g/mL at 25 °C (lit.)

SMILES 字串

C(NCc1ccccc1)c2ccccc2

InChI

1S/C14H15N/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2

InChI 密鑰

BWLUMTFWVZZZND-UHFFFAOYSA-N

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一般說明

Dibenzylamine is mainly used in the production of rubber accelerators, which play a key role in the vulcanization process. It is used as a precursor in the nitrosative cleavage of tertiary amines, aiding in various chemical reactions. It also serves as an intermediate in the synthesis of palladium complexes.

應用


  • 页岩气废水环境监测:二苄胺是页岩气废水中的有害物质之一,研究表征了其在长江上游的浓度和分布,有助于改善环境管理实践(Tang et al., 2024)。

  • 有机合成的进展:研究人员在通过大体积强制无痕区域选择性钯催化C(sp(2))-H活化的新(L)-单甲基酪氨酸合成策略中使用了二苄胺,展示了其在药物化合物开发中的实用性(Illuminati et al., 2023)。

  • 在晶体学中的应用:阐明了二苄基胺的晶体结构,为分子相互作用和在材料科学和药物设计中的潜在应用提供了见解(Sangeetha et al., 2023)。

  • 在绿色化学中的应用:二苄胺促进三唑形成反应的绿色方法,旨在通过最大限度减少环境影响和提高反应效率来开发抗癌药物(Rastogi et al., 2023)。


訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1C

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

289.4 °F - closed cup

閃點(°C)

143 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Padmarajaiah Nagaraja et al.
International journal of pharmaceutics, 235(1-2), 113-120 (2002-03-07)
Simple and sensitive spectrophotometric methods for the determination of flutamide (FLA) in either pure form or in its pharmaceutical preparations are described. The first method is based on the diazotisation of reduced FLA, followed by coupling with alcoholic iminodibenzyl (IDB)
Paul E Harrington et al.
Bioorganic & medicinal chemistry letters, 20(18), 5544-5547 (2010-08-17)
The discovery of a series of novel and orally efficacious type II calcimimetics, developed from the lead compound 1, is described herein. Compound 22 suppressed plasma PTH levels relative to vehicle when dosed orally in a rat pharmacodynamic model.
Sharad Chandrakant Deshmukh et al.
Organic & biomolecular chemistry, 10(37), 7536-7544 (2012-08-15)
A Cu(I)-catalyzed α-oxyaldehyde-dibenzylamine-alkyne coupling reaction was delineated for the construction of α-oxyamines with excellent yields and diastereoselectivity. Crystal structure analysis and theoretical calculations were also supportive of the formation of syn-α-oxyamines as the major products. Application of the methodology addresses
M B Calvo et al.
Biopharmaceutics & drug disposition, 11(9), 797-806 (1990-12-01)
The pharmacokinetics of dibenzylamine administered in a sustained drug delivery system with cefazolin was studied after i.m. administration of a dose of 1250 mg to healthy volunteers. The serum and urine levels of dibenzylamine were determined by a GLC technique
David A Fulton et al.
The Journal of organic chemistry, 67(23), 7968-7981 (2002-11-09)
An approach to the study of polyvalency-the interaction of polyvalent receptors with polyvalent ligands-in unnatural systems is outlined. In this study, the complexation of dibenzylammonium cations by dibenzo[24]crown-8 or benzometaphenylene[25]crown-8 is utilized as the component receptor-ligand interaction. Two analogous multivalent

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