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Merck

B75956

Sigma-Aldrich

4-溴苯硼酸

≥95.0%

别名:

4-溴苯基硼酸

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About This Item

线性分子式:
BrC6H4B(OH)2
CAS号:
分子量:
200.83
Beilstein:
2936347
EC號碼:
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥95.0%
95%

形狀

crystals

mp

284-288 °C (lit.)

SMILES 字串

OB(O)c1ccc(Br)cc1

InChI

1S/C6H6BBrO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H

InChI 密鑰

QBLFZIBJXUQVRF-UHFFFAOYSA-N

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應用

试剂用于
  • 钯催化 Suzuki-Miyaura 交叉偶联
  • 钯(II)催化的非对映选择性共轭加成
  • 钯催化烯丙基酯与芳基硼酸的立体选择性 Heck 型反应
  • 串联型Pd(II)催化的氧化Heck反应和分子内C-H酰胺化序列
  • 铜介导芳基硼酸与氟烷基碘的无连接有氧氟烷基化反应
  • Pd催化炔烃的碳钯化芳基环化炔烃或烯酮
  • 铜催化的交叉耦合

试剂用于制备
  • 具有潜在抗肿瘤活性的含没食子酸酯的 obovatol 类似物
  • 蛋白调节剂、酶抑制剂和激酶抑制剂

其他說明

含不定量的酸酐

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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James A Jordan-Hore et al.
Organic letters, 14(10), 2508-2511 (2012-05-02)
Ligand-free cationic Pd(II) catalyst with NaNO3 as an additive is a highly active catalytic system for conjugate additions to sterically hindered γ-substituted cyclohexenones. More challenging γγ- and βγ-substrates also react well to produce products with quaternary centers in good dr.
Synthesis of obovatol derivatives and their preliminary evaluation as antitumor agents
Lee, M.-S.; et al.
Bull. Korean Chem. Soc., 28, 1601-1604 (2007)
Tahlia R Meola et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 129, 145-153 (2018-06-02)
The synergistic effect of nanosizing and lipid-based drug delivery systems (LBDDS) was explored to enhance formulation drug loading levels and improve drug solubilisation in the gastrointestinal environment. A novel formulation combining drug nanocrystals and silica-lipid hybrid (SLH) microparticles as a
Chuan Xiao et al.
Bioorganic & medicinal chemistry, 19(23), 7100-7110 (2011-11-01)
A series of purine nucleoside analogues bearing an aryl and hetaryl group in position 6 were prepared and their biological activities were assessed by in vitro CDK1/Cyclin B1 and CDK2/Cyclin A2 kinase assay. From the synthesized chemicals, three Xylocydine derivatives
Erin Tay et al.
Pharmaceutics, 12(1) (2019-12-28)
Lipid based formulations (LBFs) are commonly employed to enhance the absorption of highly lipophilic, poorly water-soluble drugs. However, the utility of LBFs can be limited by low drug solubility in the formulation. Isolation of ionizable drugs as low melting, lipophilic

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