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Merck
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Key Documents

934100

Sigma-Aldrich

Ovine collagen

maleimide functionalized, low endotoxin

别名:

CollOvine-PEG2-MAL

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About This Item

CAS号:
分類程式碼代碼:
12352202
NACRES:
NA.28

形狀

lyophilized powder

品質等級

雜質

Bioburden, none detected
low endotoxin
≤0.1 EU/mg Endotoxin

顏色

white to off-white

官能基

maleimide

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一般說明

Collagen is a major component of the extracellular matrix (ECM) and offers low immunogenicity, a porous structure, good permeability, and biocompatibility to promote cell viability, adhesion, spreading, proliferation and differentiation.

Low endotoxin maleimide functionalized collagen derived from ovine has many biomedical applications and is a great alternative to other naturally derived materials such as those derived from bovine or porcine. Maleimide conjugations are commonly used to generate covalent conjugates with sulfhydryl containing molecules. This thiol-maleimide click chemistry reaction is commonly used for bioconjugation given its reliability, efficiency, selectivity, and preferential chemical reaction at neutral pH. The PEGylated maleimide functionalization provides methods for easy bioconjugation while maintain the advantages of the naturally derived collagen.

應用

  • 3D bioprinting
  • Tissue engineering
  • Drug delivery
  • Regenerative medicine
  • Cell culture, encapsulation, expansion and differentiation

特點和優勢

  • Certified Disease Free Sheep
  • 93-97% Type I Collagen
  • 3-7% Type III Collagen
  • 99% Purity
  • Prion Free

法律資訊

CollOvine is a trademark of OviGenex LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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