927708

2,2,11-trimethyl-4-oxo-3,8-dioxa-5,11-diazatetradecan-14-oic acid

≥95%

• 经验公式（希尔记法）: C₁₃H₂₆N₂O₅
• 分子量: 290.36
• 分類程式碼代碼: 12352106
• NACRES: NA.21

属性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder
• 反應適用性: reagent type: linker
• 官能基: carboxylic acid; ester
• 儲存溫度: 2-8°C

说明

應用

2,2,11-trimethyl-4-oxo-3,8-dioxa-5,11-diazatetradecan-14-oic acid is a heterobifunctional crosslinker useful for development of PROTAC degraders for targeted protein degradation or other bifunctional molecules in chemical biology. Incorporation of rigidity into the linker region may impact the 3D orientation of the molecules and thus ternary complex formation as well as optimization of drug-like properties. For linkers already conjugated to E3 ligase ligands, please visit our collection of Protein Degrader Building Blocks.

其他說明

Technology Article: Degrader Building Blocks for Targeted Protein Degradation

Protein Degrader Building Blocks Portal

Crosslinkers for Bioconjugation

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable