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Merck

92748

Sigma-Aldrich

对硝基苯基三甲基硅乙基碳酸酯

≥97.0%, for peptide synthesis

别名:

2-(三甲基硅基)乙基 4-硝基苯基碳酸酯, TEOC-ONp

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About This Item

经验公式(希尔记法):
C12H17NO5Si
CAS号:
分子量:
283.35
Beilstein:
4320585
EC號碼:
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.22

产品名称

对硝基苯基三甲基硅乙基碳酸酯, ≥97.0%

品質等級

化驗

≥97.0%

形狀

crystals

mp

35-40 °C

應用

peptide synthesis

官能基

carbonate
nitro

儲存溫度

2-8°C

SMILES 字串

C[Si](C)(C)CCOC(=O)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C12H17NO5Si/c1-19(2,3)9-8-17-12(14)18-11-6-4-10(5-7-11)13(15)16/h4-7H,8-9H2,1-3H3

InChI 密鑰

ZAQWGGKIMQIVGM-UHFFFAOYSA-N

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應用

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate can be used as:
  • A protecting group for an amine in one of the key synthetic steps of kottamide E total synthesis.
  • A starting material to prepare a cis-butene derivative, which is used as a polymer terminating agent in the synthesis of monotelechelic glycopolymers.

其他說明

用于引入 TEOC-氨基保护基团的试剂,TEOC-氨基保护基团可被 F- 裂解

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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其他客户在看

Slide 1 of 1

1 of 1

A. Rosowsky et al.
The Journal of Organic Chemistry, 54, 5551-5551 (1989)
L.A. Carpino et al.
Journal of the Chemical Society. Chemical Communications, 358-358 (1978)
B Wünsch et al.
Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 362(9), 1289-1292 (1981-09-01)
2-(Trimethylsilyl)ethyl-4-nitrophenyl carbonate has been prepared as a new reagent for the introduction of the 2-(trimethylsilyl)ethyloxycarbonyl group into amino acids or amino acid derivatives. The resulting N alpha-protected amino acids were found to represent suitable intermediates for the synthesis of peptides.

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