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Merck
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914010

Sigma-Aldrich

4-Nitrophenyl (2-(vinyloxy)ethyl) carbonate

≥95%

别名:

Light-initiated bioorthogonal photoclick cycloaddition reagent, VE, Vinyl ether photoclick reagent

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About This Item

经验公式（希尔记法）:
C11H11NO6
CAS号:
2257426-02-9
分子量:
253.21
分類程式碼代碼:
12352200

化驗

≥95%

形狀

liquid

儲存溫度

−20°C

應用

4-Nitrophenyl (2-(vinyloxy)ethyl) carbonate is a vinyl ether photoclick reagent (VE) mediated by visible light for bioorthogonal reaction with a 9,10-phenanthrenequinone (PQ) photoclick reagent (see cat# 913766) for increased spatiotemporal control within biological applications. Signficantly, analysis of reactivity suggests this photoclick reaction is orthogonal to azide-alkyne and UV-mediated tetrazole-ene photoclick reactions, allowing for various means of simulteneous labeling of biomolecules in a given sample. This method requires no catalyst and is reported to be compatible with cells.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

其他說明

Visible Light-Initiated Bioorthogonal Photoclick Cycloaddition

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说明
价格

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Jinbo Li et al.
Journal of the American Chemical Society, 140(44), 14542-14546 (2018-10-24)
Here we report a visible light-triggered, catalyst free bioorthogonal reaction that proceeds via a distinct pathway from reported bioorthogonal reactions. The prototype of this bioorthogonal reaction was the photocycloaddition of 9,10-phenanthrenequinone with electron-rich alkenes to form fluorogenic [4+2] cycloadducts. The

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