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Merck

902128

Sigma-Aldrich

(Z)-N′-Cyanopicolinimidamide

别名:

Weix 2-pyridyl-N-cyanocarboxamidine ligand for nickel catalysis

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About This Item

经验公式(希尔记法):
C7H6N4
CAS号:
分子量:
146.15
MDL號碼:
分類程式碼代碼:
12352111

形狀

powder or crystals

反應適用性

reagent type: catalyst
reaction type: Cross Couplings

reagent type: ligand

mp

201-205 °C

應用

This pyridyl carboxamidine ligand has been demonstrated by Daniel Weix′s lab to enable nickel-catalyzed cross-coupling of diverse basic nitrogen heterocycles with primary and secondary alkyl halides.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Eric C Hansen et al.
The Journal of organic chemistry, 82(14), 7085-7092 (2017-07-07)
Despite their importance, the synthesis of alkylated heterocycles from the cross-coupling of Lewis basic nitrogen heteroaryl halides with alkyl halides remains a challenge. We report here a general solution to this challenge enabled by a new collection of ligands based
Eric C Hansen et al.
Nature chemistry, 8(12), 1126-1130 (2016-11-23)
Ligands are essential for controlling the reactivity and selectivity of reactions catalysed by transition metals. Access to large phosphine ligand libraries has become an essential tool for the application of metal-catalysed reactions industrially, but these existing libraries are not well

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