901572

Bromo-PEG₂-acid

≥95%

• 经验公式（希尔记法）: C₇H₁₃BrO₄
• CAS号: 1807503-92-9
• 分子量: 241.08
• MDL號碼: MFCD28122969
• 分類程式碼代碼: 12352101
• NACRES: NA.22

属性

• 化驗: ≥95%
• 形狀: liquid
• 反應適用性: reagent type: linker
• 官能基: bromo; carboxylic acid
• 儲存溫度: −20°C
• SMILES 字串: BrCCOCCOCCC(O)=O

说明

應用

Bromo-PEG₂-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG₂-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility.

法律資訊

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3