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品質等級
化驗
≥95%
形狀
powder or crystals
反應適用性
reaction type: click chemistry
reagent type: cross-linking reagent
官能基
NHS ester
儲存溫度
−20°C
SMILES 字串
O=C(ON1C(CCC1=O)=O)CC(C=C2)=CC=C2C3=NN=C(C)N=N3
應用
Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
A click chemistry-based microRNA maturation assay optimized for high-throughput screening.
Lorenz D A and Garner A L
Chemical Communications (Cambridge, England), 52(53), 8267-8270 (2016)
High-Throughput Chemical Probing of Full-Length Protein?Protein Interactions.
Song J M, et al.
ACS Combinatorial Science, 19(12), 763-769 (2017)
An anti-B cell maturation antigen bispecific antibody for multiple myeloma.
Ramadoss N S, et al.
Journal of the American Chemical Society, 137(16), 5288-5291 (2015)
Biodegradable tetra-PEG hydrogels as carriers for a releasable drug delivery system.
Henise J, et al.
Bioconjugate Chemistry, 26(2), 270-278 (2015)
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