855022

无羁萜

technical grade

• 别名: 木栓酮, 软木三萜酮
• 经验公式（希尔记法）: C₃₀H₅₀O
• CAS号: 559-74-0
• 分子量: 426.72
• Beilstein: 1916451
• EC號碼: 209-205-1
• MDL號碼: MFCD00017296
• 分類程式碼代碼: 12352115
• PubChem物質ID: 24888367
• NACRES: NA.22

属性

• 等級: technical grade
• 品質等級: 100
• 形狀: solid
• mp: 262-265 °C (lit.)
• 官能基: ketone
• SMILES 字串: C[C@H]1C(=O)CC[C@@H]2[C@]1(C)CC[C@H]3[C@@]2(C)CC[C@@]4(C)[C@@H]5CC(C)(C)CC[C@]5(C)CC[C@]34C
• InChI: 1S/C30H50O/c1-20-21(31)9-10-22-27(20,5)12-11-23-28(22,6)16-18-30(8)24-19-25(2,3)13-14-26(24,4)15-17-29(23,30)7/h20,22-24H,9-19H2,1-8H3/t20-,22+,23-,24+,26+,27+,28-,29+,30-/m0/s1
• InChI 密鑰: OFMXGFHWLZPCFL-SVRPQWSVSA-N

说明

一般說明

Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor (H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent.

應用

Friedelin can be used as a starting material in the synthesis of:

• Friedel-3-enol acetate, friedel-2-oxo-3-enol acetate, friedel-2-ene derivatives and friedelin ketoxime.
• Oxygenated friedelin derivatives as potent DNA topoisomerase IIα inhibitors.
• Its 1,4-pyrazine derivatives as potent antimicrobial agents.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)