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Merck

850993

Sigma-Aldrich

2-氨基异丁酸

98%, for peptide synthesis

别名:

α-氨基异丁酸, 2-甲基丙氨酸, Aib

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About This Item

线性分子式:
(CH3)2C(NH2)COOH
CAS号:
分子量:
103.12
Beilstein:
506496
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.22

product name

2-氨基异丁酸, 98%

化驗

98%

形狀

solid

反應適用性

reaction type: solution phase peptide synthesis

mp

≥300 °C

應用

peptide synthesis

SMILES 字串

CC(C)(N)C(O)=O

InChI

1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)

InChI 密鑰

FUOOLUPWFVMBKG-UHFFFAOYSA-N

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一般說明

2-氨基异丁酸又名α-氨基丁酸,是一种氨基酸,用于液相多肽合成法。强烈促进肽形成螺旋,适合作为肽合成构件。

應用

2-氨基异丁酸可用于合成自组装多肽纳米颗粒。 结构上二-α-取代,对C−H提取呈惰性,因而在肽链中掺入这种化合物可避免发生不需要的反应。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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C Lucarelli et al.
Journal of chromatography, 541(1-2), 285-296 (1991-03-22)
A procedure is described for the determination of alpha-methyldopa (MD) [L-3-(3,4-dihydroxyphenyl)-2-methylalanine], its metabolite and catecholamines in the urine and plasma of patients undergoing MD therapy, by high-performance liquid chromatography with dual working electrode coulometric detection. An efficient sample preparation procedure
Yutong Yang et al.
Membranes, 10(11) (2020-11-14)
Amine-containing mixed-matrix membranes incorporated with amino-functionalized multi-walled carbon nanotubes (AF-MWNTs) were synthesized for CO2/H2 separation based on the facilitated transport mechanism. AF-MWNTs were chosen primarily as the mechanical reinforcing filler to enhance the membrane stability. At 107 °C and 0.2-MPa
Lucia Becucci et al.
Journal of the American Chemical Society, 132(17), 6194-6204 (2010-04-16)
Four oligopeptides consisting of a sequence of alpha-aminoisobutyric acid (Aib) residues, thiolated at either the N- or C-terminus by means of a -(CH(2))(2)-SH anchor, were self-assembled on mercury, which is a substrate known to impart a high fluidity to self-assembled
Øyvind Jacobsen et al.
The Journal of organic chemistry, 76(5), 1228-1238 (2011-02-01)
Short peptides are important as lead compounds and molecular probes in drug discovery and chemical biology, but their well-known drawbacks, such as high conformational flexibility, protease lability, poor bioavailability and short half-lives in vivo, have prevented their potential from being
Anne Goj et al.
The Journal of chemical physics, 134(20), 205103-205103 (2011-06-07)
We use mixed classical/quantum simulations to study the time dependence of an excitation of a C=O vibration on a 3-10 helix of α-aminoisobutyric acid, a system which represents a test case for the formation of self-trapped vibrational excitation states on

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